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Ugi Four-Component Reaction with Tandem Deprotection, Cyclization and Pictet–Spengler Reaction: A Concise Route to N-Fused Polycyclic Indoledi­ketopiperazine Alkaloid Analogues

หน่วยงาน Central Drug Research Institute (CDRI), India

รายละเอียด

ชื่อเรื่อง : Ugi Four-Component Reaction with Tandem Deprotection, Cyclization and Pictet–Spengler Reaction: A Concise Route to N-Fused Polycyclic Indoledi­ketopiperazine Alkaloid Analogues
นักวิจัย : Tyagi, Vikas , Khan, Shahnawaz , Chauhan, P M S
คำค้น : Indolediketopiperazine alkaloids , Ugi-multicomponent reaction , Tandem reaction , Deprotection-cyclization reactions , Pictet-Spengler reaction
หน่วยงาน : Central Drug Research Institute (CDRI), India
ผู้ร่วมงาน : -
ปีพิมพ์ : 2556
อ้างอิง : Synlett, 2013, 24 (10), 1291-1297 , http://hdl.handle.net/123456789/1402
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : CSIR-CDRI Communication No. 8434
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Aza-fused polycyclic indolediketopiperazine alkaloids are of potential interest due to their broad range of biological activities. Traditionally, a number of methods have been reported to generate N-fused polycyclic indolediketopiperazine skeletons, but the development of novel, concise methods to modify its substitution pattern are strongly required. Herein, we have described the two-step formation of N-fused polycyclic indolediketopiperazine alkaloid analogues by the application of the Ugi 4-CR with tandem deprotection-cyclization/Pictet-Spengler reaction

บรรณานุกรม :
Tyagi, Vikas , Khan, Shahnawaz , Chauhan, P M S . (2556). Ugi Four-Component Reaction with Tandem Deprotection, Cyclization and Pictet–Spengler Reaction: A Concise Route to N-Fused Polycyclic Indoledi­ketopiperazine Alkaloid Analogues.
    : Central Drug Research Institute (CDRI), India.
Tyagi, Vikas , Khan, Shahnawaz , Chauhan, P M S . 2556. "Ugi Four-Component Reaction with Tandem Deprotection, Cyclization and Pictet–Spengler Reaction: A Concise Route to N-Fused Polycyclic Indoledi­ketopiperazine Alkaloid Analogues".
    : Central Drug Research Institute (CDRI), India.
Tyagi, Vikas , Khan, Shahnawaz , Chauhan, P M S . "Ugi Four-Component Reaction with Tandem Deprotection, Cyclization and Pictet–Spengler Reaction: A Concise Route to N-Fused Polycyclic Indoledi­ketopiperazine Alkaloid Analogues."
    : Central Drug Research Institute (CDRI), India, 2556. Print.
Tyagi, Vikas , Khan, Shahnawaz , Chauhan, P M S . Ugi Four-Component Reaction with Tandem Deprotection, Cyclization and Pictet–Spengler Reaction: A Concise Route to N-Fused Polycyclic Indoledi­ketopiperazine Alkaloid Analogues. : Central Drug Research Institute (CDRI), India; 2556.