ridm@nrct.go.th   ระบบคลังข้อมูลงานวิจัยไทย   รายการโปรดที่คุณเลือกไว้

Neoflavonoids as potential osteogenic agents from Dalbergia sissoo heartwood

หน่วยงาน Central Drug Research Institute (CDRI), India

รายละเอียด

ชื่อเรื่อง : Neoflavonoids as potential osteogenic agents from Dalbergia sissoo heartwood
นักวิจัย : Kumar, Padam , Kushwaha, Priyanka , Khedgikar, Vikram , Gautam, Jyoti , Choudhary, Dharmendra , Singh, Divya , Trivedi, Ritu , Maurya, Rakesh
คำค้น : Neoflavanoids , Dalbergia Sissoo , Osteoporosis , Osteoblast
หน่วยงาน : Central Drug Research Institute (CDRI), India
ผู้ร่วมงาน : -
ปีพิมพ์ : 2557
อ้างอิง : Bioorgenic Medicinal Chemistry Letters, 2014, 24(12):2664-8 , http://hdl.handle.net/123456789/1370
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : CSIR-CDRI Communication No. 8674
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

The present study was undertaken to investigate and rationalize the in-vitro antiosteoporotic activity of neoflavonoids, isolated from Dalbergia sissoo heartwood. Neoflavonoids were isolated using extensive column chromatography and identified as dalsissooal (1) a new compound and cearoin (2), dalbergin (3), 4-methoxy dalbergion (4), dalbergiphenol (5), dalbergichromene (6), methyl dalbergin (7) and latinone (8) as known compounds by comparison their spectroscopic data with those reported in the literature. Among the screened compounds, compounds 1, 3, 5-8 significantly increased proliferation as assessed by alkaline phosphatase activity and mineralization in calvarial osteoblast cells.

บรรณานุกรม :
Kumar, Padam , Kushwaha, Priyanka , Khedgikar, Vikram , Gautam, Jyoti , Choudhary, Dharmendra , Singh, Divya , Trivedi, Ritu , Maurya, Rakesh . (2557). Neoflavonoids as potential osteogenic agents from Dalbergia sissoo heartwood.
    : Central Drug Research Institute (CDRI), India.
Kumar, Padam , Kushwaha, Priyanka , Khedgikar, Vikram , Gautam, Jyoti , Choudhary, Dharmendra , Singh, Divya , Trivedi, Ritu , Maurya, Rakesh . 2557. "Neoflavonoids as potential osteogenic agents from Dalbergia sissoo heartwood".
    : Central Drug Research Institute (CDRI), India.
Kumar, Padam , Kushwaha, Priyanka , Khedgikar, Vikram , Gautam, Jyoti , Choudhary, Dharmendra , Singh, Divya , Trivedi, Ritu , Maurya, Rakesh . "Neoflavonoids as potential osteogenic agents from Dalbergia sissoo heartwood."
    : Central Drug Research Institute (CDRI), India, 2557. Print.
Kumar, Padam , Kushwaha, Priyanka , Khedgikar, Vikram , Gautam, Jyoti , Choudhary, Dharmendra , Singh, Divya , Trivedi, Ritu , Maurya, Rakesh . Neoflavonoids as potential osteogenic agents from Dalbergia sissoo heartwood. : Central Drug Research Institute (CDRI), India; 2557.