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Development of quality control markers for Ulmus wallichiana Planchon: A Indian traditional plant for osteogenic activity

หน่วยงาน Central Drug Research Institute (CDRI), India

รายละเอียด

ชื่อเรื่อง : Development of quality control markers for Ulmus wallichiana Planchon: A Indian traditional plant for osteogenic activity
นักวิจัย : Arya, K R , Khatoon, Sayyada , Kumar, Brijesh
คำค้น : Ulmus wallichiana , Bone healing , Q TOF HRMS , Quality control marker , HPTLC
หน่วยงาน : Central Drug Research Institute (CDRI), India
ผู้ร่วมงาน : -
ปีพิมพ์ : 2556
อ้างอิง : Indian Journal of Traditional Knowledge, 2013, 12(4), 664-669 , http://hdl.handle.net/123456789/1377
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : CSIR-CDRI Communication No. 8466
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Ulmus wallichiana Planchon, is an Indian folk traditional plant used for the treatment of fractured bones in folklore tradition of Uttarakhand Himalaya, India. During chemical investigations, three major compounds, Ulmoside A & B, and Naringenin-6-C-β-D glucopyranosideis for osteogenic activity have been isolated from bark of this plant species. This paper presents macro and microscopic study, physicochemical parameters and chemo-profiling of stem bark of U. wallichiana through Q TOF HRMS for development of quality control markers and identification of crude samples. Transverse section (TS) stem bark and powder microscopy shows crushed rhytidoma consisting plenty of mucilaginous canals followed by crushed cork, cells of the cork filled with dark brown content. Whereas, authenticity and quality of raw materials can be determinate with exact calculated mass value of marker compounds for osteogenic activity at 467, 451 and 435 using Q TOF HRMS technique. Ursolic acid, β-sitosterol and lupeol at Rf value 0.25, 0.36 and 0.44 has also identified as HPTLC marker for identification and authentication of crude drug samples of stem bark of U. wallichiana.

บรรณานุกรม :
Arya, K R , Khatoon, Sayyada , Kumar, Brijesh . (2556). Development of quality control markers for Ulmus wallichiana Planchon: A Indian traditional plant for osteogenic activity.
    : Central Drug Research Institute (CDRI), India.
Arya, K R , Khatoon, Sayyada , Kumar, Brijesh . 2556. "Development of quality control markers for Ulmus wallichiana Planchon: A Indian traditional plant for osteogenic activity".
    : Central Drug Research Institute (CDRI), India.
Arya, K R , Khatoon, Sayyada , Kumar, Brijesh . "Development of quality control markers for Ulmus wallichiana Planchon: A Indian traditional plant for osteogenic activity."
    : Central Drug Research Institute (CDRI), India, 2556. Print.
Arya, K R , Khatoon, Sayyada , Kumar, Brijesh . Development of quality control markers for Ulmus wallichiana Planchon: A Indian traditional plant for osteogenic activity. : Central Drug Research Institute (CDRI), India; 2556.