ชื่อเรื่อง | : | Tandem Cu-Catalyzed Ketenimines formation and Intramolecular Nucleophile Capture: Synthesis of 1,2-dihydro-2-Iminoquinolines from 1-(o-acetamidophenyl)-Propargyl Alcohols |
นักวิจัย | : | kumar, G R , Kumar, Y K , Kant, Ruchir , Reddy, M S |
คำค้น | : | Alkyne , Azide , Cycloaddition , Cyclization , Quinoline |
หน่วยงาน | : | Central Drug Research Institute (CDRI), India |
ผู้ร่วมงาน | : | - |
ปีพิมพ์ | : | 2557 |
อ้างอิง | : | Beilstein Journa of Organic Chemistry, 2014, 10, 1255–1260 , http://hdl.handle.net/123456789/1374 |
ที่มา | : | - |
ความเชี่ยวชาญ | : | - |
ความสัมพันธ์ | : | CSIR-CDRI Communication No. 8678 |
ขอบเขตของเนื้อหา | : | - |
บทคัดย่อ/คำอธิบาย | : | The copper catalyzed ketenimine formation reaction of 1-(o-acetamidophenyl)-propargyl alcohols with various sulfonyl azides is found to undergo a concomitant intramolecular nucleophile attack to generate 1,2-dihydro-2-iminoquinolines after aromatization (via elimination of acetyl and hydroxyl groups) and tautomerization. The reaction produces 4-substituted and 3,4-unsubstituted title compounds in moderate to good yields under mild reaction conditions. |
บรรณานุกรม | : |
kumar, G R , Kumar, Y K , Kant, Ruchir , Reddy, M S . (2557). Tandem Cu-Catalyzed Ketenimines formation and Intramolecular Nucleophile Capture: Synthesis of 1,2-dihydro-2-Iminoquinolines from 1-(o-acetamidophenyl)-Propargyl Alcohols.
: Central Drug Research Institute (CDRI), India. kumar, G R , Kumar, Y K , Kant, Ruchir , Reddy, M S . 2557. "Tandem Cu-Catalyzed Ketenimines formation and Intramolecular Nucleophile Capture: Synthesis of 1,2-dihydro-2-Iminoquinolines from 1-(o-acetamidophenyl)-Propargyl Alcohols".
: Central Drug Research Institute (CDRI), India. kumar, G R , Kumar, Y K , Kant, Ruchir , Reddy, M S . "Tandem Cu-Catalyzed Ketenimines formation and Intramolecular Nucleophile Capture: Synthesis of 1,2-dihydro-2-Iminoquinolines from 1-(o-acetamidophenyl)-Propargyl Alcohols."
: Central Drug Research Institute (CDRI), India, 2557. Print. kumar, G R , Kumar, Y K , Kant, Ruchir , Reddy, M S . Tandem Cu-Catalyzed Ketenimines formation and Intramolecular Nucleophile Capture: Synthesis of 1,2-dihydro-2-Iminoquinolines from 1-(o-acetamidophenyl)-Propargyl Alcohols. : Central Drug Research Institute (CDRI), India; 2557.
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