ridm@nrct.go.th   ระบบคลังข้อมูลงานวิจัยไทย   รายการโปรดที่คุณเลือกไว้

Factors affecting retention and resolution of hydrophobic aromatic compounds in microemulsion electrokinetic chromatography

หน่วยงาน จุฬาลงกรณ์มหาวิทยาลัย

รายละเอียด

ชื่อเรื่อง : Factors affecting retention and resolution of hydrophobic aromatic compounds in microemulsion electrokinetic chromatography
นักวิจัย : Kieatsuda Poouthree
คำค้น : Capillary electrophoresis , Aromatic compounds , Separation ‪(Technology)‬ , Chromatographic analysis
หน่วยงาน : จุฬาลงกรณ์มหาวิทยาลัย
ผู้ร่วมงาน : Thumnoon Nhujak , Natchanun Leepipatpiboon , Chulalongkorn University. Faculty of Science
ปีพิมพ์ : 2549
อ้างอิง : http://cuir.car.chula.ac.th/handle/123456789/11859
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Thesis (Ph.D.)--Chulalongkorn University, 2006

Retention behaviors, such as retention factor (k) and retention index (I), of homologous series compounds in microemulsion electrokinetic chromatography (MEEKC) with suppressed electroosmosis were investigated. Using alkylbenzenes (BZ) as standard, the retention indices of other homologous series compounds are independent of the concentration of sodium dodecyl sulphate ([SDS]) and temperature, while dependent on the type and concentration of organic co-solvents (phi). The retention factor increases with increasing [SDS], while decreases with increasing temperature or phi. At a given ([SDS]) and phi, excellent agreement was found between the observed and predicted values of log k of analytes in MEEKC, where the predicted values were obtained from our modified equations. Using BZ as standards, excellent agreement is found between predicted and literature values of log K[subscript ow] of the test analytes, where K[subscript ow] is the octanol-water distribution constant of the analyte. In addition, the resolution (R[subscript s]) in MEEKC and micellar electrokinetic chromatography (MEKC) was compared using bisphenol-A-diglycidlyl ether and its derivatives as test analytes. Separation scales were compared using a resolution equation, R[subscript s] = (N[superscript0.5]/4)(a-1)/(1+ k[subscript 2]), where a is the selectivity (a = k[subscript 2]/ k[subscript 1] for k[subscript 2][is more than or equal to] k[subscript 1]>0), and N the theaverage efficiency. At a given [SDS], phi and temperature, in comparison with MEKC, MEEKC was found to give better resolution of analytes, mainly due to the significantly smaller k in MEEKC, but not the greater a in MEEKC, while a comparable range of N.

บรรณานุกรม :
Kieatsuda Poouthree . (2549). Factors affecting retention and resolution of hydrophobic aromatic compounds in microemulsion electrokinetic chromatography.
    กรุงเทพมหานคร : จุฬาลงกรณ์มหาวิทยาลัย.
Kieatsuda Poouthree . 2549. "Factors affecting retention and resolution of hydrophobic aromatic compounds in microemulsion electrokinetic chromatography".
    กรุงเทพมหานคร : จุฬาลงกรณ์มหาวิทยาลัย.
Kieatsuda Poouthree . "Factors affecting retention and resolution of hydrophobic aromatic compounds in microemulsion electrokinetic chromatography."
    กรุงเทพมหานคร : จุฬาลงกรณ์มหาวิทยาลัย, 2549. Print.
Kieatsuda Poouthree . Factors affecting retention and resolution of hydrophobic aromatic compounds in microemulsion electrokinetic chromatography. กรุงเทพมหานคร : จุฬาลงกรณ์มหาวิทยาลัย; 2549.