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Focal brain damage protects against post-traumatic stress disorder in combat veterans

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Focal brain damage protects against post-traumatic stress disorder in combat veterans
นักวิจัย : Koenigs, Michael , Huey, Edward D , Raymont, Vanessa , Cheon, Bobby , Solomon, Jeffrey , Wassermann, Eric M , Grafman, Jordan
คำค้น : DRNTU::Science::Biological sciences::Human anatomy and physiology::Neurobiology
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2551
อ้างอิง : Koenigs, M., Huey, E. D., Raymont, V., Cheon, B., Solomon, J., Wassermann, E., et al. (2008). Focal brain damage protects against post-traumatic stress disorder in combat veterans. Nature neuroscience, 11, 232-237. , http://hdl.handle.net/10220/24225 , http://dx.doi.org/10.1038/nn2032 , 182502
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Nature neuroscience
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Post-traumatic stress disorder (PTSD) is an often debilitating mental illness that is characterized by recurrent distressing memories of traumatic events. PTSD is associated with hypoactivity in the ventromedial prefrontal cortex (vmPFC), hyperactivity in the amygdala and reduced volume in the hippocampus, but it is unknown whether these neuroimaging findings reflect the underlying cause or a secondary effect of the disorder. To investigate the causal contribution of specific brain areas to PTSD symptoms, we studied a unique sample of Vietnam War veterans who suffered brain injury and emotionally traumatic events. We found a substantially reduced occurrence of PTSD among those individuals with damage to one of two regions of the brain: the vmPFC and an anterior temporal area that included the amygdala. These results suggest that the vmPFC and amygdala are critically involved in the pathogenesis of PTSD.

บรรณานุกรม :
Koenigs, Michael , Huey, Edward D , Raymont, Vanessa , Cheon, Bobby , Solomon, Jeffrey , Wassermann, Eric M , Grafman, Jordan . (2551). Focal brain damage protects against post-traumatic stress disorder in combat veterans.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Koenigs, Michael , Huey, Edward D , Raymont, Vanessa , Cheon, Bobby , Solomon, Jeffrey , Wassermann, Eric M , Grafman, Jordan . 2551. "Focal brain damage protects against post-traumatic stress disorder in combat veterans".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Koenigs, Michael , Huey, Edward D , Raymont, Vanessa , Cheon, Bobby , Solomon, Jeffrey , Wassermann, Eric M , Grafman, Jordan . "Focal brain damage protects against post-traumatic stress disorder in combat veterans."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2551. Print.
Koenigs, Michael , Huey, Edward D , Raymont, Vanessa , Cheon, Bobby , Solomon, Jeffrey , Wassermann, Eric M , Grafman, Jordan . Focal brain damage protects against post-traumatic stress disorder in combat veterans. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2551.