ชื่อเรื่อง | : | Associations between serum lipids and causes of mortality in a cohort of 3499 Urban Thais : the Electricity Generating Authority of Thailand (EGAT) study |
นักวิจัย | : | Piyamitr Sritara , Prisana Patoomanunt , Woodward, Mark Lee , Kulaya Narksawat , Supoj Tulyadachanon , Wipa Ratanachaiwong , Chanika Sritara , Barzi, Federica , Sukit Yamwong , Supachai Tanomsup |
คำค้น | : | - |
หน่วยงาน | : | สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์ |
ผู้ร่วมงาน | : | - |
ปีพิมพ์ | : | 2551 |
อ้างอิง | : | Angiology. 58,6 (2008) pp. 757-763 , http://dspace.library.tu.ac.th/handle/3517/1317 |
ที่มา | : | - |
ความเชี่ยวชาญ | : | - |
ความสัมพันธ์ | : | - |
ขอบเขตของเนื้อหา | : | - |
บทคัดย่อ/คำอธิบาย | : | The association between serum lipids and mortality has not previously been established in Thailand. Baseline data from the Electricity Generating Authority of Thailand (EGAT) cohort study, plus a resurvey of the cohort 15 years later were analyzed. Participants were employees of EGAT: 2702 men and 797 women. Total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), and triglycerides (TG) were taken as predictive variables; age, sex, hypertension, diabetes, cigarette smoking, alcohol drinking, and body mass index were taken as confounders. Dependent variables were all-causes and specific causes of mortality over 17 years of follow-up. The major cause of death among men was cardiovascular disease (CVD); among women, it was cancer. Relative risks (RR) for specific causes of death, for a mmol/L increase in each lipid, were estimated after adjustment for confounding factors using Cox proportional hazards regression. TC and LDL-C were negatively associated with liver cirrhosis mortality, although it was likely that the low cholesterol concentration was a consequence of the disease. HDL-C was negatively associated with CVD mortality (RR = 0.59; 95% confidence interval [CI], 0.39-0.93), coronary heart disease (CHD) mortality (RR = 0.36; 95% CI, 0.17-0.75) and all cause-mortality (RR = 0.68; 95% CI, 0.54-0.87). TG was not associated with mortality. HDL-C is an important risk factor for CVD in middle-class urban Thais. Health promotion programs to improve lipid profiles, such as effective exercise campaigns and dietary advice, are required to increase HDL-C and to help prevent CVD and premature death in Thailand. |
บรรณานุกรม | : |
Piyamitr Sritara , Prisana Patoomanunt , Woodward, Mark Lee , Kulaya Narksawat , Supoj Tulyadachanon , Wipa Ratanachaiwong , Chanika Sritara , Barzi, Federica , Sukit Yamwong , Supachai Tanomsup . (2551). Associations between serum lipids and causes of mortality in a cohort of 3499 Urban Thais : the Electricity Generating Authority of Thailand (EGAT) study.
กรุงเทพมหานคร : สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์ . Piyamitr Sritara , Prisana Patoomanunt , Woodward, Mark Lee , Kulaya Narksawat , Supoj Tulyadachanon , Wipa Ratanachaiwong , Chanika Sritara , Barzi, Federica , Sukit Yamwong , Supachai Tanomsup . 2551. "Associations between serum lipids and causes of mortality in a cohort of 3499 Urban Thais : the Electricity Generating Authority of Thailand (EGAT) study".
กรุงเทพมหานคร : สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์ . Piyamitr Sritara , Prisana Patoomanunt , Woodward, Mark Lee , Kulaya Narksawat , Supoj Tulyadachanon , Wipa Ratanachaiwong , Chanika Sritara , Barzi, Federica , Sukit Yamwong , Supachai Tanomsup . "Associations between serum lipids and causes of mortality in a cohort of 3499 Urban Thais : the Electricity Generating Authority of Thailand (EGAT) study."
กรุงเทพมหานคร : สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์ , 2551. Print. Piyamitr Sritara , Prisana Patoomanunt , Woodward, Mark Lee , Kulaya Narksawat , Supoj Tulyadachanon , Wipa Ratanachaiwong , Chanika Sritara , Barzi, Federica , Sukit Yamwong , Supachai Tanomsup . Associations between serum lipids and causes of mortality in a cohort of 3499 Urban Thais : the Electricity Generating Authority of Thailand (EGAT) study. กรุงเทพมหานคร : สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์ ; 2551.
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