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Adaptation of marine derived fungus Chaetomium globosum (NIOCC 36) to alkaline stress using antioxidant properties

หน่วยงาน National Institute Of Oceanography (NIO), India

รายละเอียด

ชื่อเรื่อง : Adaptation of marine derived fungus Chaetomium globosum (NIOCC 36) to alkaline stress using antioxidant properties
นักวิจัย : Ravindran, C. , Naveenan, T.
คำค้น : Antioxidants , Marine fungi , Free radical , Chaetomium globosum
หน่วยงาน : National Institute Of Oceanography (NIO), India
ผู้ร่วมงาน : -
ปีพิมพ์ : 2554
อ้างอิง : Process Biochemistry, vol.46; 2011; 847-857 , http://drs.nio.org/drs/handle/2264/3813
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

The fungi are an exceptionally useful model in elucidating the cell functions under extreme conditions (temperature, salinity, and pH values) and mechanisms underlying adaptation to those extreme environmental conditions. Here, Chaetomium globosum was examined for its adaptation mechanism under alkaline stress using antioxidant properties. The aqueous extracts of C. globosum exhibited different levels of antioxidant activity in all the in vitro tests such as alpha, alpha-diphenyl-beta-picrylhydrazyl (DPPH), hydrogen peroxide, hydroxyl radical scavenging assay (HRSA), ferric reducing/antioxidant power (FRAP) assay, metal chelating assay and beta-carotene-linolic acid model system. The antioxidant capacity of marine fungi showed an increase in activity with increase in stress. In addition, the production of intra and extracellular antioxidant enzymes of the fungus at various pH stresses were analyzed and discussed for their possible role in the stress mechanism. The present study elucidates that the scavenging activity is one of the protective mechanisms developed to avoid the deleterious effect of stress. Furthermore, the in vitro assays also clearly indicate that fungal extracts are significant source of natural antioxidant, which might be helpful in preventing the progress of various oxidative stresses

บรรณานุกรม :
Ravindran, C. , Naveenan, T. . (2554). Adaptation of marine derived fungus Chaetomium globosum (NIOCC 36) to alkaline stress using antioxidant properties.
    : National Institute Of Oceanography (NIO), India.
Ravindran, C. , Naveenan, T. . 2554. "Adaptation of marine derived fungus Chaetomium globosum (NIOCC 36) to alkaline stress using antioxidant properties".
    : National Institute Of Oceanography (NIO), India.
Ravindran, C. , Naveenan, T. . "Adaptation of marine derived fungus Chaetomium globosum (NIOCC 36) to alkaline stress using antioxidant properties."
    : National Institute Of Oceanography (NIO), India, 2554. Print.
Ravindran, C. , Naveenan, T. . Adaptation of marine derived fungus Chaetomium globosum (NIOCC 36) to alkaline stress using antioxidant properties. : National Institute Of Oceanography (NIO), India; 2554.