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Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence

หน่วยงาน Universiti Sains Malaysia, Malaysia

รายละเอียด

ชื่อเรื่อง : Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence
นักวิจัย : Ibrahim, Baharudin , Mostafa, Hamza , M. Amin, Arwa , Arif, Nor Hayati , Murugaiyah, Vikneswaran
คำค้น : RS1-441 Pharmacy and materia medica
หน่วยงาน : Universiti Sains Malaysia, Malaysia
ผู้ร่วมงาน : -
ปีพิมพ์ : 2560
อ้างอิง : http://eprints.usm.my/37096/1/(Nuclear_magnetic_resonance)_39%2D2%2D3.pdf , Mostafa, Hamza and M. Amin, Arwa and Arif, Nor Hayati and Murugaiyah, Vikneswaran and Ibrahim, Baharudin (2017) Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence. Songklanakarin journal of Science & Technology, 39 (2). pp. 153-162. ISSN 0125-3395
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : https://www.researchgate.net/publication/316545518_Nuclear_magnetic_resonance_spectroscopy_based_metabolomics_to_identify_novel_biomarkers_of_alcohol-dependence , http://eprints.usm.my/37096/
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Alcohol misuse is a ravaging public health and social problem. Its harm can affect the drinkers and the whole society. Alcohol-dependence is a phase of alcohol misuse in which the drinker consumes excessive amounts of alcohol and has a continuous urge to consume alcohol. Current methods of alcohol dependence diagnoses are questionnaires and some biomarkers. However, both methods lack specificity and sensitivity. Metabolomics is a scientific field which deals with the identification and the quantification of the metabolites present in the metabolome using spectroscopic techniques such as nuclear magnetic resonance (NMR). Metabolomics helps to indicate the perturbation in the levels of metabolites in cells and tissues due to diseases or ingestion of any substances. NMR is one of the most widely used spectroscopic techniques in metabolomics because of its reproducibility and speed. Some recent metabolomics studies were conducted on alcohol consumption and alcohol misuse in animals and humans. However, few focused on identifying alcohol dependence novel biomarkers. A sensitive and specific technique such as NMR based metabolomics applied to find novel biomarkers in plasma and urine can be useful to diagnose alcohol-dependence.

บรรณานุกรม :
Ibrahim, Baharudin , Mostafa, Hamza , M. Amin, Arwa , Arif, Nor Hayati , Murugaiyah, Vikneswaran . (2560). Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence.
    กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia.
Ibrahim, Baharudin , Mostafa, Hamza , M. Amin, Arwa , Arif, Nor Hayati , Murugaiyah, Vikneswaran . 2560. "Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence".
    กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia.
Ibrahim, Baharudin , Mostafa, Hamza , M. Amin, Arwa , Arif, Nor Hayati , Murugaiyah, Vikneswaran . "Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence."
    กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia, 2560. Print.
Ibrahim, Baharudin , Mostafa, Hamza , M. Amin, Arwa , Arif, Nor Hayati , Murugaiyah, Vikneswaran . Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence. กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia; 2560.